Reference interval for immature platelet fraction on Sysmex XN haematology analyser in adult population

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Reference interval for immature platelet fraction on Sysmex XN haematology analyser in adult population

Introduction The Sysmex XN-series haematology analyser has newly adopted a fluorescent channel to measure immature platelet fraction (IPF). To promote the clinical utility of this promising parameter, establishing a reliable reference interval is mandatory. According to previous studies, IPF values may be affected by the employed analyser and the ethnic background of the individual, but no diff...

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Immature platelet fraction measured on the Sysmex XN hemocytometer predicts thrombopoietic recovery after autologous stem cell transplantation

OBJECTIVES A period of thrombocytopenia is common after stem cell transplantation (SCT). To prevent serious bleeding complications, prophylactic platelet transfusions are administered. Previous studies have shown that a rise in immature platelets precedes recovery of platelet count. Our aim was to define a cutoff value for immature platelets predicting thrombopoietic recovery within 2 d. METH...

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Immature platelet fraction: establishment of a reference interval and diagnostic measure for thrombocytopenia.

BACKGROUND Immature platelet fraction (IPF, %) is a measure of reticulated platelets (RPs), which represents the state of thrombopoiesis. The IPF is obtained from an automated hematology analyzer as one of the platelet parameters. This study was performed to establish reference intervals of IPF and its cut-off values for the differential diagnosis of thrombocytopenia. METHODS Blood samples fr...

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The immature platelet fraction (IPF) in neonates

Young (immature) platelets containing residual RNA, so-called reticulated thrombocytes, appear in the peripheral blood after the release from bone marrow. It has been shown that the count of the reticulated platelet correlates with the megakaryocyte mass. As of late, the immature platelet fraction (IPF) may be reliably quantified with the fully automated blood analyzer Sysmex XE-2100. IPF may b...

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Mean Platelet Volume and Immature Platelet Fraction in Autoimmune Disorders

Mean platelet volume (MPV), measured using automated blood analysers, has been appraised as a potential biomarker in cardiovascular disease, diabetes mellitus, and cancer. The test, a useful tool in differentiation of thrombocytopenic states, has now been carried out for autoimmune disorders, but data are yet scarce. Controversial results have been obtained in systemic and organ-specific autoim...

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ژورنال

عنوان ژورنال: Biochemia Medica

سال: 2018

ISSN: 1330-0962,1846-7482

DOI: 10.11613/bm.2018.010708